Evaluation of the immunomodulatory activity of thalidomide on tumor-associated macrophages in the 4T1 murine metastatic breast cancer model
ABSTRACT The present work evaluated the immunomodulatory effect of thalidomide (Thal) at different doses on tumor-associated macrophages (TAMs) using a mouse model of human breast cancer.Mice were inoculated with 4T1 cells in the Cleaning Gloves left flank and treated with Thal once a day at concentrations of 50, 100, and 150mg/kg body weight from